Copper/Iron‐Cocatalyzed Cascade Perfluoroalkylation/Cyclization of 1,6‐Enynes with Iodoperfluoroalkanes.

Abstract: A copper/iron‐cocatalyzed fluoroalkylative cyclization of 1,6‐enynes with readily available iodoperfluoroalkanes reagents for the synthesis of the corresponding fluoroalkylated pyrrolidines and benzofuran derivatives is reported. This novel protocol provides a mild method for the construction of C<italic>sp</italic>3‐CF2 and exocyclic double bonds in one step with high regio‐ and stereo‐selectivities. [ABSTRACT FROM AUTHOR]