Back to Search
Start Over
MANSC: a seven-cysteine-containing domain present in animal membrane and extracellular proteins
- Source :
-
Trends in Biochemical Sciences . Apr2004, Vol. 29 Issue 4, p172. 3p. - Publication Year :
- 2004
-
Abstract
- MANSC (motif at N terminus with seven cysteines) is a novel domain with a well-conserved seven-cysteine motif that is present at the N terminus of membrane and extracellular proteins, including low-density lipoprotein receptor-related protein 11 (LRP-11), hepatocyte growth factor activator inhibitor 1 (HAI-1) and some uncharacterized proteins encoded by multicellular animals from Mollusca to Chordata. We postulate that the MANSC domain in HAI-1 might function through binding with hepatocyte growth factor activator and matriptase. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 09680004
- Volume :
- 29
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Trends in Biochemical Sciences
- Publication Type :
- Academic Journal
- Accession number :
- 12777075
- Full Text :
- https://doi.org/10.1016/j.tibs.2004.02.007