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Chromatin regulation and immune escape: Deficiency in a chromatin remodeling complex enhances tumor immunotherapy.

Authors :
Ghorani, Ehsan
Quezada, Sergio A.
Source :
Science. 2/16/2018, Vol. 359 Issue 6377, p745-746. 2p. 1 Diagram.
Publication Year :
2018

Abstract

The article reports on the study that found the contribution of chromatin remodeling pathways to cancer cell immune resistance. Topics mentioned include the regulation of the interferon-stimulated gene (ISG) expression, the target on the pathways that could enhance tumor immunotherapy, and the antitumor effects of interferons (IFNs).

Details

Language :
English
ISSN :
00368075
Volume :
359
Issue :
6377
Database :
Academic Search Index
Journal :
Science
Publication Type :
Academic Journal
Accession number :
128059441
Full Text :
https://doi.org/10.1126/science.aat0383