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A model of immunomodulatory for dengue infection mm.

Authors :
Zulfa, Annisa
Handayani, Dewi
Nuraini, Nuning
van Heijster
Quam
Handayani
Source :
AIP Conference Proceedings. 2018, Vol. 1937 Issue 1, p1-1. 1p. 1 Graph.
Publication Year :
2018

Abstract

An immunomodulatory model for dengue infection is constructed in this paper. This study focuses on T-cell compartments and B cells that are immune cells involved in the dengue infection process. Dengue virus-infected monocyte cells release interferons to signal T-cells to activate B-cells and produce antibodies. Immunomodulator acts as a treatment control and aims to increase the numbers of antibodies so it is expected to reduce the number of infected monocyte cells by dengue virus. Numerical simulation shows that the greater the rate of <italic>f</italic> (<italic>t</italic>) the immune cells will be stimulated to suppress the number of infected cells. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
0094243X
Volume :
1937
Issue :
1
Database :
Academic Search Index
Journal :
AIP Conference Proceedings
Publication Type :
Conference
Accession number :
128323790
Full Text :
https://doi.org/10.1063/1.5026096