Back to Search
Start Over
Graphene blended with SnO2 and Pd-Pt nanocages for sensitive non-enzymatic electrochemical detection of H2O2 released from living cells.
- Source :
-
Analytica Chimica Acta . Jul2018, Vol. 1014, p10-18. 9p. - Publication Year :
- 2018
-
Abstract
- This paper described a novel, facile and nonenzymatic electrochemical biosensor to detect hydrogen peroxide (H 2 O 2 ). The sensor was fabricated based on Pd-Pt nanocages and SnO 2 /graphene nanosheets modified electrode (PdPt NCs@SGN/GCE). The electrochemical behavior of PdPt NCs@SGN/GCE exhibited excellent catalytic activity toward H 2 O 2 with fast response, high selectivity, superior sensitivity, low detection limit of 0.3 μM and large linear range from 1 μM to 300 μM. Under these obvious advantages, the constructed biosensor provided to be reliable for determination of H 2 O 2 secreted from human cervical cancer cells (Hela cells). Hence, the proposed biosensor is a promising candidate for detection of H 2 O 2 in situ released from living cells in clinical diagnostics. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00032670
- Volume :
- 1014
- Database :
- Academic Search Index
- Journal :
- Analytica Chimica Acta
- Publication Type :
- Academic Journal
- Accession number :
- 128390259
- Full Text :
- https://doi.org/10.1016/j.aca.2018.01.067