Back to Search
Start Over
Ultra-low-dose lung screening CT with model-based iterative reconstruction: an assessment of image quality and lesion conspicuity.
- Source :
-
Acta Radiologica . May2018, Vol. 59 Issue 5, p553-559. 7p. - Publication Year :
- 2018
-
Abstract
- Background Reducing radiation dose inevitably increases image noise, and thus, it is important in low-dose computed tomography (CT) to maintain image quality and lesion detection performance. Purpose To assess image quality and lesion conspicuity of ultra-low-dose CT with model-based iterative reconstruction (MBIR) and to determine a suitable protocol for lung screening CT. Material and Methods A total of 120 heavy smokers underwent lung screening CT and were randomly and equally assigned to one of five groups: group 1 = 120 kVp, 25 mAs, with FBP reconstruction; group 2 = 120 kVp, 10 mAs, with MBIR; group 3 = 100 kVp, 15 mAs, with MBIR; group 4 = 100 kVp, 10 mAs, with MBIR; and group 5 = 100 kVp, 5 mAs, with MBIR. Two radiologists evaluated intergroup differences with respect to radiation dose, image noise, image quality, and lesion conspicuity using the Kruskal-Wallis test and the Chi-square test. Results Effective doses were 61-87% lower in groups 2-5 than in group 1. Image noises in groups 1 and 5 were significantly higher than in the other groups ( P < 0.001). Overall image quality was best in group 1, but diagnostic acceptability of overall image qualities in groups 1-3 was not significantly different (all P values > 0.05). Lesion conspicuities were similar in groups 1-4, but were significantly poorer in group 5. Conclusion Lung screening CT with MBIR obtained at 100 kVp and 15 mAs enables a ∼60% reduction in radiation dose versus low-dose CT, while maintaining image quality and lesion conspicuity. [ABSTRACT FROM AUTHOR]
- Subjects :
- *LUNG injuries
*IMAGE quality analysis
*RADIATION doses
*IMAGE reconstruction
*COMPUTED tomography
*COMPARATIVE studies
*DIAGNOSTIC imaging
*LONGITUDINAL method
*LUNG diseases
*RESEARCH methodology
*MEDICAL cooperation
*COMPUTERS in medicine
*RESEARCH
*EVALUATION research
*RANDOMIZED controlled trials
*MEDICAL artifacts
Subjects
Details
- Language :
- English
- ISSN :
- 02841851
- Volume :
- 59
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Acta Radiologica
- Publication Type :
- Academic Journal
- Accession number :
- 128547755
- Full Text :
- https://doi.org/10.1177/0284185117726099