Two Antibody-Producing Cell Types in Four Species.

Authors :: Avrameas, S.
Kuhlmann, W.
Miller, H.R.P.
Leduc, Elizabeth
Source :: Immunology. Jan71, Vol. 20 Issue 1, p85-89. 5p.
Publication Year :: 1971
Abstract: Both differentiating plasma cells and modified lymphocytes (lympho-plasmocytes) synthesize specific humoral antibody in rabbits, rats, mice and guinea-pigs. They do so during both primary and secondary responses, after subcutaneous injection of three enzymic antigens: horse radish peroxidase, glucose oxidase and alkaline phosphatase, administered as soluble or insolubilized proteins or alum precipitated or mixed with Freund's adjuvant. [ABSTRACT FROM AUTHOR]