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Regulation of Carotene Biosynthesis in <em>Phycomyces</em> by Vitamin A and <em>β</em>-Ionone.
- Source :
-
European Journal of Biochemistry . Oct74 Part 2, Vol. 48 Issue 2, p617-623. 7p. - Publication Year :
- 1974
-
Abstract
- The presence of vitamin A in the medium results in a large increase in Β-carotene content in wild-type Phycomyces blakesleeanus; in carB mutants. which accumulate phytoene. and carR mutants. which accumulate lycopene, the presence of vitamin A results in an increase in these intermediates. In carA mutants. which usually form no carotenoids. vitamin A partially counteracts the mutational block and allows Β-carotene synthesis. Vitamin A is not itself converted to Β-carotene. Β-ionone. long known as a stimulator of carotenogenesis, can also counteract carA mutations. The effects of vitamin A and Β-ionone do not occur in the presence of the protein-synthesis inhibitor cycloheximide. Vitamin A and Β-ionone stimulate carotenogenesis through the normal pathway. probably by interaction with the carA gene product. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00142956
- Volume :
- 48
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- European Journal of Biochemistry
- Publication Type :
- Academic Journal
- Accession number :
- 12906594
- Full Text :
- https://doi.org/10.1111/j.1432-1033.1974.tb03804.x