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Acenocoumarol as an alternative anticoagulant in a patient with warfarin‐related nephropathy.
- Source :
-
British Journal of Clinical Pharmacology . May2018, Vol. 84 Issue 5, p1068-1071. 4p. 1 Color Photograph, 1 Chart, 1 Graph. - Publication Year :
- 2018
-
Abstract
- Adverse Event: Warfarin‐related nephropathy. Drug Implicated: Warfarin. The Patient: A 31‐year‐old female, managed with warfarin for rheumatic heart disease with atrial fibrillation. Evidence that Links the Drug to the Event: There were no alternative causes of nephropathy that could have caused the adverse event in this patient. Management: Shifting the drug from warfarin to acenocoumarol. Mechanism: Difference in renal elimination between warfarin and acenocoumarol. Implication for Therapy: Clinicians should be aware of this rare adverse effect of warfarin, and acenocoumarol can be considered as an alternative therapy for this condition. Hypotheses to be Tested: Further prospectively designed studies are needed to consider acenocoumarol as an alternative therapy in warfarin‐related nephropathy. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 03065251
- Volume :
- 84
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- British Journal of Clinical Pharmacology
- Publication Type :
- Academic Journal
- Accession number :
- 129134337
- Full Text :
- https://doi.org/10.1111/bcp.13541