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Exogenous human herpesvirus 6 reinfection after tumor-infiltrating T-lymphocyte therapy.

Authors :
Filippova, Anastasiia
Charles, Julie
Epaulard, Olivier
Germi, Raphaƫle
Persoons, Virginie
Templier, Isabelle
Leccia, Marie-Therese
Dreno, Brigitte
Malova, Irina
Morand, Patrice
Lupo, Julien
Source :
Cytotherapy (Elsevier Inc.). Apr2018, Vol. 20 Issue 4, p521-523. 3p.
Publication Year :
2018

Abstract

Exogenous human herpes virus 6 (HHV-6) reinfection has never been reported in patients receiving tumor-infiltrating T lymphocytes therapy. We report an unusual case of HHV-6 infection following infusion of HHV-6 infected autologous T lymphocytes. HHV-6 infection could interfere with the tumor antigen immune recognition and the efficacy of immunotherapy. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14653249
Volume :
20
Issue :
4
Database :
Academic Search Index
Journal :
Cytotherapy (Elsevier Inc.)
Publication Type :
Academic Journal
Accession number :
129152853
Full Text :
https://doi.org/10.1016/j.jcyt.2017.12.006