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An MTH1-targeted nanosystem for enhanced PDT via improving cellular sensitivity to reactive oxygen species.
- Source :
-
Chemical Communications . 4/25/2018, Vol. 54 Issue 34, p4310-4313. 4p. - Publication Year :
- 2018
-
Abstract
- Herein, we developed a strategy to attack the cancer cell defense system against reactive oxygen species to improve photodynamic therapy efficacy with a Ce6@MSN@MTH1 siRNA nanosystem, which was demonstrated to improve cellular sensitivity to reactive oxygen species through suppressing MTH1 protein in cancer cells. [ABSTRACT FROM AUTHOR]
- Subjects :
- *REACTIVE oxygen species
*PHOTODYNAMIC therapy
*PHOSPHATASES
Subjects
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 54
- Issue :
- 34
- Database :
- Academic Search Index
- Journal :
- Chemical Communications
- Publication Type :
- Academic Journal
- Accession number :
- 129296463
- Full Text :
- https://doi.org/10.1039/c8cc01841c