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Prospects of IL-2 in Cancer Immunotherapy.

Authors :
Choudhry, Hani
Helmi, Nawal
Abdulaal, Wesam H.
Zeyadi, Mustafa
Zamzami, Mazin A.
Wu, Wei
Mahmoud, Maged Mostafa
Warsi, Mohiuddin Khan
Rasool, Mahmood
Jamal, Mohammad S.
Source :
BioMed Research International. 5/6/2018, Vol. 2018, p1-7. 7p.
Publication Year :
2018

Abstract

IL-2 is a powerful immune growth factor and it plays important role in sustaining T cell response. The potential of IL-2 in expanding T cells without loss of functionality has led to its early use in cancer immunotherapy. IL-2 has been reported to induce complete and durable regressions in cancer patients but immune related adverse effects have been reported (irAE). The present review discusses the prospects of IL-2 in immunotherapy for cancer. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
23146133
Volume :
2018
Database :
Academic Search Index
Journal :
BioMed Research International
Publication Type :
Academic Journal
Accession number :
129461398
Full Text :
https://doi.org/10.1155/2018/9056173