Stereodivergent synthesis of novel chiral C2-symmetric bis-trifluoromethyl-2-oxazolidinones.

Authors :: Remarchuk, Travis
Corey, E.J.
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Jun2018, Vol. 59 Issue 23, p2256-2259. 4p.
Publication Year :: 2018
Abstract: A simplified effective synthetic process is described for the diastereoselective synthesis of the chiral C 2 -symmetric CF 3 -ureas ( R,R )- 15 and ( S,S )- 15 from ( S )-α-phenylethylamine, glyoxal and CF 3 I. [ABSTRACT FROM AUTHOR]

Subjects :: *CHIRALITY
*CHEMICAL synthesis
*TRIFLUOROMETHYL compounds
*OXAZOLIDINONES
*PHENETHYLAMINES
*GLYOXAL

Language :: English
ISSN :: 00404039
Volume :: 59
Issue :: 23
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 129607236
Full Text :: https://doi.org/10.1016/j.tetlet.2018.04.072

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