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A chromene pyrazoline derivatives fluorescent probe for Zn2+ detection in aqueous solution and living cells.
- Source :
-
Inorganica Chimica Acta . Jul2018, Vol. 479, p128-134. 7p. - Publication Year :
- 2018
-
Abstract
- A new chromene pyrazoline derivatives fluorescent probe L was designed and synthesized. The probe L appears in a 55-fold fluorescence enhancement after 5 equiv. Zn 2+ was added, and it also exhibits high sensitivity and selectivity for response to Zn 2+ in ethanol-water (V:V = 1:1) solution through “OFF-ON” type process and a possible photoinduced electron transfer (PET). Notably, the probe L distinguishes between Zn 2+ and Cd 2+ . The association constant was considered as 2.38 × 10 3 M −1 via fluorescence titration experiments. The probe L-Zn 2+ complex forms a 1:1 binding stoichiometry which was discussed by Job’s plot. The probe is very highly sensitive with fluorometric detection limit of 1.603 × 10 −10 M. It also shows good reversibility upon addition of EDTA. Furthermore, the viability of L to Zn 2+ has practical application in live cell imaging. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00201693
- Volume :
- 479
- Database :
- Academic Search Index
- Journal :
- Inorganica Chimica Acta
- Publication Type :
- Academic Journal
- Accession number :
- 129734755
- Full Text :
- https://doi.org/10.1016/j.ica.2018.04.020