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Phytochemicals and Antimicrobial Activities of Rumex nervosus Natural Populations Grown in Sarawat Mountains, Kingdom of Saudi Arabia.
- Source :
-
Arabian Journal for Science & Engineering (Springer Science & Business Media B.V. ) . Jul2018, Vol. 43 Issue 7, p3465-3476. 12p. - Publication Year :
- 2018
-
Abstract
- Rumex nervosus, common weed plant in Sarawat Mountains, Saudi Arabia, belongs to family Polygonaceae and usually used as traditional herbal medicines. In the current study, R. nervosus plants dissected into roots, stems, leaves, and flowers that collected from seven locations in Aseer region, Kingdom of Saudi Arabia. The antimicrobial activity of methanol and n-hexane extracts was investigated against three pathogenic bacterial strains and one pathogenic fungus by using agar well-diffusion method. The phytochemicals and vitamins content present in the methanol extracts was investigated by using gas chromatography-mass spectrometry (GC-MS) analysis and high-performance liquid chromatography (HPLC). The results revealed that all extracts showed significant activity against tested microbes. Methanol extracts demonstrated the highest degree of antimicrobial inhibition activity as compared with n-hexane extracts. The root extracts exhibited the highest inhibitory activity against the tested microbes. The GC-MS and HPLC indicated the presence of numerous phytochemicals in the different parts of R. nervosus as well as a set of vitamins including vitamins B1,B2,B12<inline-graphic></inline-graphic>, and folic acid. In conclusion, the present study showed that methanol and n-hexane extracts of all parts of R. nervosus could be used as promising alternative drugs to treat bacterial and Candida spp. infections. [ABSTRACT FROM AUTHOR]
- Subjects :
- *RUMEX
*ANTI-infective agents
*THERAPEUTICS
Subjects
Details
- Language :
- English
- ISSN :
- 2193567X
- Volume :
- 43
- Issue :
- 7
- Database :
- Academic Search Index
- Journal :
- Arabian Journal for Science & Engineering (Springer Science & Business Media B.V. )
- Publication Type :
- Academic Journal
- Accession number :
- 129812175
- Full Text :
- https://doi.org/10.1007/s13369-018-3136-z