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[11C]Methionine emerges as a new biomarker for tracking active myeloma lesions.

Authors :
Lapa, Constantin
Schreder, Martin
Lückerath, Katharina
Samnick, Samuel
Rudelius, Martina
Buck, Andreas K.
Kortüm, Klaus M.
Einsele, Hermann
Rosenwald, Andreas
Knop, Stefan
Source :
British Journal of Haematology. Jun2018, Vol. 181 Issue 5, p701-703. 3p. 1 Black and White Photograph, 1 Chart.
Publication Year :
2018

Abstract

The article discusses a prospective study which investigated the emergence of L-methyl-C methionine (MET) as a new biomarker for monitoring active myeloma lesions. Involved in the study were ten patients with biopsy-proven multiple myeloma who underwent molecular imaging using positron emission tomography (PET) with a radiolabelled glucose analogue for diagnosis. The study has shown the potential superiority of the amino acid MET for staging multiple myeloma.

Details

Language :
English
ISSN :
00071048
Volume :
181
Issue :
5
Database :
Academic Search Index
Journal :
British Journal of Haematology
Publication Type :
Academic Journal
Accession number :
129857319
Full Text :
https://doi.org/10.1111/bjh.14696