Thiazonaphthalimide derivatives: Synthesis and interaction with DNA.

Authors :: Botz, Alexandra
Chenavier, Yves
Pécaut, Jacques
Delangle, Pascale
Gateau, Christelle
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Jun2018, Vol. 59 Issue 26, p2550-2553. 4p.
Publication Year :: 2018
Abstract: The synthesis of several thiazonaphthalimide derivatives is described. The exclusive formation of angular rather than linear isomers was unequivocally demonstrated by NMR and single crystal X-ray diffraction. Their photophysical properties and ability to bind calf-Thymus DNA with affinities in the range of 10 4 makes them interesting candidates to probe DNA by fluorescence. [ABSTRACT FROM AUTHOR]

Subjects :: *CHEMICAL synthesis
*ISOMERS
*FLUORESCENCE
*NUCLEAR magnetic resonance
*SINGLE crystals
*X-ray diffraction

Language :: English
ISSN :: 00404039
Volume :: 59
Issue :: 26
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 129946619
Full Text :: https://doi.org/10.1016/j.tetlet.2018.05.052