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An analytical poroelastic model for laboratorial mechanical testing of the articular cartilage (AC).
- Source :
-
Applied Mathematics & Mechanics . Jun2018, Vol. 39 Issue 6, p813-828. 16p. - Publication Year :
- 2018
-
Abstract
- The articular cartilage (AC) can be seen as a biphasic poroelastic material. The cartilage deformation under compression mainly leads to an interstitial fluid flow in the porous solid phase. In this paper, an analytical poroelastic model for the AC under laboratorial mechanical testing is developed. The solutions of interstitial fluid pressure and velocity are obtained. The results show the following facts. (i) Both the pressure and fluid velocity amplitudes are proportional to the strain loading amplitude. (ii) Both the amplitudes of pore fluid pressure and velocity in the AC depend more on the loading amplitude than on the frequency. Thus, in order to obtain the considerable fluid stimulus for the AC cell responses, the most effective way is to increase the loading amplitude rather than the frequency. (iii) Both the interstitial fluid pressure and velocity are strongly affected by permeability variations. This model can be used in experimental tests of the parameters of AC or other poroelastic materials, and in research of mechanotransduction and injury mechanism involved interstitial fluid flow. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 02534827
- Volume :
- 39
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Applied Mathematics & Mechanics
- Publication Type :
- Academic Journal
- Accession number :
- 129951713
- Full Text :
- https://doi.org/10.1007/s10483-018-2334-9