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Electrochemical sensing of attomolar miRNA combining cascade strand displacement polymerization and reductant-mediated amplification.
- Source :
-
Chemical Communications . 7/7/2018, Vol. 54 Issue 53, p7366-7369. 4p. - Publication Year :
- 2018
-
Abstract
- Herein, we have developed a distinctive electrochemical sensing platform for miRNA assay. Target miRNA initiates two cycles of polymerization, nicking, and displacement reactions, which lead to the variation of the distance between redox molecules and the electrode surface. In addition, a reductant is employed for further electrochemical amplification. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ELECTROCHEMICAL sensors
*POLYMERIZATION
*MICRORNA
Subjects
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 54
- Issue :
- 53
- Database :
- Academic Search Index
- Journal :
- Chemical Communications
- Publication Type :
- Academic Journal
- Accession number :
- 130392143
- Full Text :
- https://doi.org/10.1039/c8cc03698e