钆塞酸二钠在肝细胞癌诊断中的价值.

Gd-EOB-DPTA is a hepatocyte-specific contrast agent with the function of double-contrast imaging. It can reflect the blood supply of lesions via dynamic enhancement imaging and show the change in the expression of molecular receptors on hepatocyte membrane via hepatobiliary phase imaging. Gd-EOB-DPTA can reflect the multistep process of hepatocarcinogenesis from multiple dimensions, improve detection of hypovascular hepatocellular carcinoma (HCC) and small HCC, display cirrhotic nodules with high-risk malignant transformation, and therefore, it has been recommended as a noninvasive tool for HCC diagnosis in China and international HCC clinical practice guidelines. This article reviews the recent advances of Gd-EOB-DTPA in the diagnosis of HCC. [ABSTRACT FROM AUTHOR]