Synthesis of 1‐Aminoindenes through Aza‐Prins‐Type Cyclization.

Abstract: An acid‐catalyzed aza‐Prins‐type endo cyclization of 2‐alkenylbenzaldehydes with BocNH2 or aniline derivatives through in situ generation of iminium intermediates has been developed, and various 1‐aminoindene derivatives were readily obtained. The first catalytic asymmetric variant of the present reaction has also been demonstrated. [ABSTRACT FROM AUTHOR]