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Sedoanalgesia con ketofol vs propofol-fentanilo en pacientes sometidos a procedimientos endoscópicos.
- Source :
-
Archivos Venezolanos de Farmacología y Terapéutica . 2018, Vol. 37 Issue 2, p110-114. 5p. - Publication Year :
- 2018
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Abstract
- Introduction: The objective of this study was to compare the efficacy of Ketofol sedoanalgesia with respect to that obtained with Propofol-fentanyl combination in patients undergoing endoscopic procedures at Hopsital Coromoto from Maracaibo, Zulia state. Materials and methods: A experimental, interventional, comparative study was carried out with a probabilistic sample in 60 patients undergoing digestive endoscopic procedure, which were randomly assigned to be treated with Ketofol (group A: n=30) or Propofol-Fentanyl (group B: n=30). The evaluation of the general characteristics, hemodynamic modifications, Ramsay Scale, Consciousness Recovery Time and Visual Analogous Scale was performed. Results: There were no differences according to the pharmacological group evaluated. Ketofol showed a lower transoperative variability in mean arterial pressure values (Ketofol: 77.3±12.4 vs Propofol Fentanyl: 66.8±8.9; p<0.01) and O2 Saturation (Ketofol: 96, 0±2.2 vs Propofol Fentanyl: 92.7±3.5; p<0.01), with similar Ramsay and VAS score between both groups. Conclusions: this study demonstrates the efficacy and safety of ketofol in the sedoanalgesia of patients undergoing endoscopic study when compared with the propofol-fentanyl combination, representing a novel anesthetic strategy to be specifically explored on a large scale. [ABSTRACT FROM AUTHOR]
Details
- Language :
- Spanish
- ISSN :
- 07980264
- Volume :
- 37
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Archivos Venezolanos de Farmacología y Terapéutica
- Publication Type :
- Academic Journal
- Accession number :
- 130892374