Flow chemistry-enabled studies of rhodium-catalyzed hydroformylation reactions.

Authors :: Zhu, Cheng
Raghuvanshi, Keshav
Coley, Connor W.
Mason, Dawn
Rodgers, Jody
Janka, Mesfin E.
Abolhasani, Milad
Source :: Chemical Communications. 8/11/2018, Vol. 54 Issue 62, p8567-8570. 4p.
Publication Year :: 2018
Abstract: We present an automated microscale flow chemistry platform for rapid performance evaluation of continuous and discrete reaction parameters in homogeneous hydroformylation reactions. We demonstrate the versatility of the developed microfluidic platform through a systematic study of the effects of a library of phosphine-based ligands on catalytic activity and regioselectivity. [ABSTRACT FROM AUTHOR]