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Global Stability of Within-Host Virus Dynamics Models with Multitarget Cells.

Authors :
Elaiw, Ahmed M.
Alade, Taofeek O.
Alsulami, Saud M.
Source :
Mathematics (2227-7390). Jul2018, Vol. 6 Issue 7, p118. 1p.
Publication Year :
2018

Abstract

In this paper, we study the stability analysis of two within-host virus dynamics models with antibody immune response. We assume that the virus infects <italic>n</italic> classes of target cells. The second model considers two types of infected cells: (i) latently infected cells; and (ii) actively infected cells that produce the virus particles. For each model, we derive a biological threshold number R 0 . Using the method of Lyapunov function, we establish the global stability of the steady states of the models. The theoretical results are confirmed by numerical simulations. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
22277390
Volume :
6
Issue :
7
Database :
Academic Search Index
Journal :
Mathematics (2227-7390)
Publication Type :
Academic Journal
Accession number :
131048301
Full Text :
https://doi.org/10.3390/math6070118