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The study of redox mechanism of dobutamine at different pH media by electrochemical and in situ spectroelectrochemical methods
- Source :
-
Electrochimica Acta . Aug2004, Vol. 49 Issue 19, p3121-3127. 7p. - Publication Year :
- 2004
-
Abstract
- Based on the comprehensive analyses of the experimental results of the electrochemical methods, in situ UV-Vis absorption spectra, in situ electron spin resonance (ESR), and attenuated total-internal reflection (ATR) as well as the calculation of UV-Vis absorption data by PM3 Semi-Empirical method, a reaction mechanism for the redox processes of dobutamine was presented. When the anodic sweep is carried out, dobutamine firstly undergoes a free radical reaction with one-electron and one-proton to form semi-quinone free radicals, which will continuously convert to its corresponding quinone form by further electrochemical oxidation reaction. The formed quinone cannot only undergo a cyclization process by chemical reaction to produce a new compound, which can be reduced at more negative potential, but also be reduced to form dobutamine again when subsequent cathodic sweep is followed. The cyclization rate is depended upon pH values, and it increases with the increase of pH. In neutral medium, the corresponding oxidation form of the cyclization reaction product is easy to convert to melanin. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 00134686
- Volume :
- 49
- Issue :
- 19
- Database :
- Academic Search Index
- Journal :
- Electrochimica Acta
- Publication Type :
- Academic Journal
- Accession number :
- 13106598
- Full Text :
- https://doi.org/10.1016/j.electacta.2004.02.026