An efficient synthesis of biaryl diamides via Ullmann coupling reaction catalyzed by CuI in the presence of Cs2CO3 and TBAB.

Abstract: CuI accompanyied by Cs2CO3 and TBAB was confirmed to be an efficient catalyst combination to promote an Ullmann coupling reaction. It facilitated 2-bromobenzamides to undergo a coupling reaction for the synthesis of symmetrical biaryldiamides in moderate yields at 120 °C under Pd-free conditions.Graphical Abstract: <graphic></graphic> [ABSTRACT FROM AUTHOR]