Visual analysis of retinal changes with optical coherence tomography.

Optical coherence tomography (OCT) enables noninvasive high-resolution 3D imaging of the human retina, and thus plays a fundamental role in detecting a wide range of ocular diseases. Despite the diagnostic value of OCT, managing and analyzing resulting data is challenging. We apply two visual analysis strategies for supporting retinal assessment in practice. First, we provide an interface for unifying and structuring data from different sources into a common basis. Fusing that basis with medical records and augmenting it with analytically derived information facilitates thorough investigations. Second, we present a tailored visual analysis tool for presenting, emphasizing, selecting, and comparing different aspects of the attributed data. This enables free exploration, reducing the data to relevant subsets, and focusing on details. By applying both strategies, we effectively enhance the management and the analysis of retinal OCT data for assisting medical diagnoses. Domain experts applied our solution successfully to study early retinal changes in patients suffering from type 1 diabetes mellitus. [ABSTRACT FROM AUTHOR]