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Photopatterned salecan composite hydrogel reinforced with α-Mo2C nanoparticles for cell adhesion.
- Source :
-
Carbohydrate Polymers . Nov2018, Vol. 199, p119-128. 10p. - Publication Year :
- 2018
-
Abstract
- Salecan, a water-soluble extracellular β-glucan, has emerged as a promising candidate for preparing hydrogel biomaterials recently. Herein, photo cross linked composite hydrogels, composed by salecan/poly ( N-tert -butylacrylamide-co-acrylamide) network andα-Mo 2 C nanoparticles were prepared by ultraviolet (UV) light, using Irgacue 2959 as photo initiator. The XRD and EDX analysis illustrated the presence of embeddedα-Mo 2 C nanoparticles throughout the hydrogel matrix. Compression tests and thermal analysis revealed that the incorporation of α-Mo 2 C nanoparticles enhanced mechanical strength and thermal stability due to the structural reinforcement of the composite hydrogels. Moreover, the change of salecan content provided a mean to tailor both the swelling property and morphology of the composite hydrogels. Encapsulation of L929 and 3T3-L1 cells and the following viability test showed the excellent cell-compatibility of these hydrogels. Taken together, these studies support the use of photo crosslinked composite hydrogels as tunable biomaterials for cell adhesion. [ABSTRACT FROM AUTHOR]
- Subjects :
- *HYDROGELS
*NANOPARTICLE synthesis
*CELL adhesion
*BIOMATERIALS
*X-ray diffraction
Subjects
Details
- Language :
- English
- ISSN :
- 01448617
- Volume :
- 199
- Database :
- Academic Search Index
- Journal :
- Carbohydrate Polymers
- Publication Type :
- Academic Journal
- Accession number :
- 131355422
- Full Text :
- https://doi.org/10.1016/j.carbpol.2018.07.005