Zobrazení periferních nervů pomocí difuzního tenzoru a MR traktografie.

Aim: Development of an examination protocol for investigation of functional integrity and microstructural damage of peripheral nerves (PN) at different locations using diffusion tensor imagi ng (DTI). Consequently, we want to implement this protocol into clinical practice. Subjects and methods: We investigated 15 healthy volunteers and 15 patients with a 3T MRI, scanner usi ng the DTI method. We attempted to visualize the brachial plexus, lumbosacral plexus and the course of PN in the limbs of healthy volunteers. In patients, we focused on the examination of damaged parts of the PN to display these pathologies. Results: We managed to obtain a valid visualization of the brachial plexus, lumbosacral plexus and the course of PN in the limbs us i ng DTI. Throughout the study, we encountered some limitations of this method, particularly motion artifacts which interfered with the quality of nerve structure imaging and problems in differentiating nerve fibers from muscle fibers. These technical problems could be reduced to a certain extent using adequate coils, optimizing imaging protocols and data processing methodology. Conclusion: Despite some technical limitations, this paper demonstrates the possibility of obtaini ng a valid display of PN in different locations us i ng the DTI method. DTI is an additional non-invasive imagi ng technique providi ng valuable information useful in the decision-maki ng diagnostic and therapeutic process for various PN pathologies. Technological advances and further improvements of MRI techniques in the future are likely to result in a wider use of this technique in clinical practice. [ABSTRACT FROM AUTHOR]