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Renal epithelioid angiomyolipoma: magnetic resonance imaging characteristics.
- Source :
-
Abdominal Radiology . Oct2018, Vol. 43 Issue 10, p2756-2763. 8p. 1 Black and White Photograph, 3 Diagrams, 2 Charts. - Publication Year :
- 2018
-
Abstract
- Objective: The aim of the study was to analyze MR imaging features of renal epithelioid angiomyolipoma (EAML).Methods: This study included 17 patients with histopathologically confirmed renal EAML who underwent renal MRI scanning before radical or partial nephrectomy. MR images were retrospectively reviewed and correlated with pathological findings.Result: Fifteen lesions (88.2%) appeared as round or oval. The tumor-kidney interface was round in 14 lesions (82.4%). Fifteen tumors (88.2%) presented mainly isointensity on T1WI, and eleven tumors (64.7%) presented mainly hypointensity on T2WI. Twelve lesions (70.6%) showed restricted diffusion on DWI, and the mean ADC value was 1.23 ± 0.28 × 10−3mm2/s. Minimal fat component was identified as loss of signal intensity on opposed-phase MR images in 6 cases (35.3%). Sixteen lesions (100%) demonstrated inhomogeneous enhancement, and 7 of 16 masses (43.8%) showed reticular enhancement. Rapid wash-in and wash-out enhancement was seen in 13 masses (81.3%). In the corticomedullary phase, the mass showed markedly enhancement in 14 cases (87.5%). The irregular vessels and hemorrhage were detected in 4 cases (23.5%) and 7 cases (41.2%), respectively. One patient (5.9%) had a lymph node involvement at initial diagnosis, and showed distant metastasis after operation. In the immunohistochemical analysis, 15 tumors (88.2%) were positive for melanocytic marker (HMB45 or Melan-A), and all cases (100%) were negative for epithelial-associated markers (CK or AE1/AE3).Conclusion: The presence of hypointensity on T2WI, restricted diffusion on DWI, round tumor-kidney interface, reticular, and marked enhancement (rapid wash-in and wash-out) should further raise suspicion for renal EAML. The diagnosis may be confirmed by pathological analysis. [ABSTRACT FROM AUTHOR]
- Subjects :
- *MAGNETIC resonance imaging
*ANGIOMYOLIPOMA
*PATHOLOGY
*KIDNEY tumors
*METASTASIS
Subjects
Details
- Language :
- English
- ISSN :
- 2366004X
- Volume :
- 43
- Issue :
- 10
- Database :
- Academic Search Index
- Journal :
- Abdominal Radiology
- Publication Type :
- Academic Journal
- Accession number :
- 131640977
- Full Text :
- https://doi.org/10.1007/s00261-018-1548-6