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Ultrasound Parameters for Human Osteoarthritic Subchondral Bone ex Vivo: Comparison with Micro-Computed Tomography Parameters.
- Source :
-
Ultrasound in Medicine & Biology . Oct2018, Vol. 44 Issue 10, p2115-2130. 16p. - Publication Year :
- 2018
-
Abstract
- The aim of this study was to identify ultrasound parameters reflecting subchondral porosity (Po), subchondral plate thickness (Tpl) and bone volume fraction at the trabecular bone region (BV/TVTb). Sixteen osteoarthritic human lateral femoral condyles were evaluated ex vivo using a 15-MHz pulsed-echo ultrasound 3-D scanning system. The cartilage-subchondral bone (C-B) surface region (layer 1) and inner subchondral bone region (layer 2) were analyzed; we newly introduced entropy (ENT) and correlation (COR) of ultrasound texture parameters of the parallel (x) or perpendicular (z) direction to the C-B interface for this analysis. Po, Tpl and BV/TVTb were evaluated as reference measurements using micro-computed tomography. ENTL1x (ENT of layer 1, x-direction) and ENTL1z were significantly correlated with Po (both r values = 0.58), CORL2x with Tpl (r = -0.73) and CORL2z with BV/TVTb (r = -0.66). These are efficient indicators of the characteristics of osteoarthritis-related subchondral bone; the other texture parameters were not significant. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 03015629
- Volume :
- 44
- Issue :
- 10
- Database :
- Academic Search Index
- Journal :
- Ultrasound in Medicine & Biology
- Publication Type :
- Academic Journal
- Accession number :
- 131690133
- Full Text :
- https://doi.org/10.1016/j.ultrasmedbio.2018.06.003