Back to Search
Start Over
Enantioselective Construction of Silicon‐Stereogenic Silanes by Scandium‐Catalyzed Intermolecular Alkene Hydrosilylation.
- Source :
-
Angewandte Chemie . 9/17/2018, Vol. 130 Issue 38, p12522-12526. 5p. - Publication Year :
- 2018
-
Abstract
- Abstract: The catalytic asymmetric construction of silicon‐stereogenic silanes is of great interest and significance, but has met with only limited success to date. We herein report the enantioselective hydrosilylation of alkenes with dihydrosilanes by a chiral half‐sandwich scandium catalyst, which constitutes an efficient and general route for the synthesis of a wide range of enantioenriched silicon‐stereogenic silanes from easily accessible starting materials. This reaction features a broad substrate scope, high yields, and high enantioselectivity. Some of the chiral tertiary silane products were also converted into valuable derivatives, such as chiral silanol, quaternary silane, and benzosilole compounds. [ABSTRACT FROM AUTHOR]
- Subjects :
- *CHEMICAL reactions
*CARBONYL compounds
*HYDROSILYLATION
*SCANDIUM
*SILANOLS
Subjects
Details
- Language :
- English
- ISSN :
- 00448249
- Volume :
- 130
- Issue :
- 38
- Database :
- Academic Search Index
- Journal :
- Angewandte Chemie
- Publication Type :
- Academic Journal
- Accession number :
- 131719931
- Full Text :
- https://doi.org/10.1002/ange.201807493