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Fabrication of carbonate apatite blocks from octacalcium phosphate blocks through different phase conversion mode depending on carbonate concentration.
- Source :
-
Journal of Solid State Chemistry . Nov2018, Vol. 267, p85-91. 7p. - Publication Year :
- 2018
-
Abstract
- Abstract Carbonate apatite (CO 3 Ap) is an inorganic component of mature bone and is used as bone substitute instead of autografts. Recently, 100% pure CO 3 Ap granules formed from calcium carbonate via a dissolution-precipitation reaction have been used as a clinical precursor for bone. In this study, the feasibility of fabricating blocks of CO 3 Ap from blocks of octacalcium phosphate (OCP), which is an analog of the bone composition and serves as a precursor for bone, was investigated by immersion in NaHCO 3. The macroscopic structure of the OCP block was retained upon conversion to CO 3 Ap. In addition, as the NaHCO 3 concentration increased from 0.0 to 2.0 mol/L, the carbonate content increased in the resulting CO 3 Ap, reaching ≈ 14 wt% at maximum NaHCO 3 concentration. Moreover, the morphology of the CO 3 Ap crystals varied as the NaHCO 3 concentration increased up to 0.5 mol/L: they were pseudomorphic plate-like when the NaHCO 3 concentration was low but formed particles ranging ~ 10 nm in size at high NaHCO 3 concentrations. The different phase transformation modes depended on NaHCO 3 concentrations closely related to CO 3 Ap crystal morphology and were associated with a decrease in the mechanical strength of the block. Graphical abstract Different phase conversion modes from OCP to CO 3 Ap depended on CO 3 concentration fx1 [ABSTRACT FROM AUTHOR]
- Subjects :
- *APATITE
*PHOSPHATES
*SCAFFOLDING
*DISSOLUTION (Chemistry)
*PSEUDOMORPHS
Subjects
Details
- Language :
- English
- ISSN :
- 00224596
- Volume :
- 267
- Database :
- Academic Search Index
- Journal :
- Journal of Solid State Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 131730942
- Full Text :
- https://doi.org/10.1016/j.jssc.2018.08.008