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Formation of organosilica nanoparticles with dual functional groups and simultaneous payload entrapment.
- Source :
-
Journal of Microencapsulation . Jun2018, Vol. 35 Issue 4, p381-391. 11p. - Publication Year :
- 2018
-
Abstract
- A mixed organosilane system for simultaneous formation of organosilica nanoparticles has been systematically studied for loading of various compounds with a wide range of log P values. The molecule-entrapping system was understood by investigating the effects of adjusting various experimental parameters on particle formation and molecule entrapment. Particularly, rhodamine 6 G (R6G) loaded colloidal particles were prepared and characterised in detail. The results show that whereas most molecules had entrapment efficiency (EE%) in the range of 20-80%, R6G exhibited near 100% efficiency. Moreover, the colloidal system can be tuned to incorporate R6G with the extent of entrapment spanning at least 2 orders of magnitude (i.e. from 0.04 to 4 mg) and a maximum EE% of 98%. In conclusion, the study demonstrates the promise of the proposed mixed organosilane system in forming colloidal particles containing multiple functional groups with selective loading of highly hydrophobic molecules. [ABSTRACT FROM AUTHOR]
- Subjects :
- *NANOPARTICLES
*SILICONES
*HYDROPHOBIC compounds
*FUNCTIONAL groups
*COLLOIDS
Subjects
Details
- Language :
- English
- ISSN :
- 02652048
- Volume :
- 35
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Journal of Microencapsulation
- Publication Type :
- Academic Journal
- Accession number :
- 131778696
- Full Text :
- https://doi.org/10.1080/02652048.2018.1508314