Kardiyak Cerrahi Sonrası Mortalite; BNP, EuroSCORE ve SOFA Skoru Kıyaslanması.

Objective: Mortality after cardiac surgery is between 2.94% and 30.7%. In our study, we aimed to compare the significance and the discriminative power of preoperative brain natriuretic peptide (pre BNP), the first 3 days of SOFA, and maximum Sequential Failure Assessment (SOFA) and European System for Cardiac Operative Risk Evaluation (EuroSCORE) in the estimation of long- term mortality in patients who underwent elective isolated coronary artery bypass graft (CABG) operation. Material and Methods: Ethical committee approved our retrospective study. We searched 173 patients who underwent CABG between 2007 and 2009. Patients without blood test results or medical records; those who underwent emergent, additive surgery or different surgical techniques (off-pump); cases that could not be fully mobilized, individuals with left ventricular function below 30%; pulmonary hipertension and those died in operation theatre or within 60 days after surgery were excluded from the study. Thus, 40 out of 173 patients aged between 45, and 80 years were included in the study. BNP blood tests were performed. EuroSCORE scores were calculated from computerized preoperative data Preoperative SOFA scores were measured from patient's data recorded in ICU within postoperative first 24 hours (0-24hr SOFA0), 24-48hr (SOFA1), and 48-72hr (SOFA2), maximum score of 3 days (maxSOFA). SPSS 15.0 was used. Obtained results were evaluated within 95% confidence interval and the level of significance was accepted as p<0.05. Results: SOFA1 scores in exited cases are more significant than EuroSCORE scores when compared with those survived. (SOFA1 p<0.05, EuroSCORE p=0.06). There is a positive correlation between preBNP and SOFA1 (p<0.05), SOFA2 (p<0.01) and EuroSCORE (p<0.01) scores. According to area under curve in ROC analysis (AUC) SOFA1 was evaluated as "very good"(AUC: 0.764, p=0.02), and EuroSCORE as "good" (AUC: 0.727, p=0.05) in the prediction of mortality. Conclusion: To the best of our knowledge,SOFA score has not been compared with preBNP in the evaluation of mortality. Higher SOFA scores, and preBNP values are correlated with mortality in patients with CABG. In our study, we found that SOFA1 is more significant than the other mortality prediction methods in the long term mortality of the patients following CABG. [ABSTRACT FROM AUTHOR]