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Photoinduced C—C Bond Cleavage and Oxidation of Cycloketoxime Esters.
- Source :
-
Chinese Journal of Chemistry . Nov2018, Vol. 36 Issue 11, p995-999. 5p. - Publication Year :
- 2018
-
Abstract
- A novel structural reorganization of cycloketoxime esters beyond the traditional Beckmann rearrangement process has been established to build cyano‐containing ketones in the presence of photocatalyst. This novel transformation is remarkable with selective C—C bond cleavage and an oxidation process enabled by DMSO used as the solvent, oxidant, and oxygen source avoiding acid, base and toxic cyanide salts as the cyano source. Further applications in late‐stage modification of complex and chiral molecules have also been reported. A SET‐induced strategy has been established for C—C bond cleavage and oxidation sequence of cycloketoxime esters in the presence of photocatalyst. The protocol is distinguished by mild and safe reaction conditions that avoid peroxide, acid, base and toxic cyanide salts. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 1001604X
- Volume :
- 36
- Issue :
- 11
- Database :
- Academic Search Index
- Journal :
- Chinese Journal of Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 132394088
- Full Text :
- https://doi.org/10.1002/cjoc.201800206