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Early stages of infection of three‐spined stickleback (Gasterosteus aculeatus) with the cestode Schistocephalus solidus.

Authors :
Wohlleben, Anika Marie
Franke, Frederik
Hamley, Madeleine
Kurtz, Joachim
Scharsack, Jörn Peter
Source :
Journal of Fish Diseases. Nov2018, Vol. 41 Issue 11, p1701-1708. 8p.
Publication Year :
2018

Abstract

Parasitic helminths have evolved strategies to evade their host's immune systems. Particularly, the early time of interactions between helminths and their hosts might be decisive for their infection success. We used the cestode Schistocephalus solidus, and its highly specific second intermediate host, the three‐spined stickleback (Gasterosteus aculeatus) to investigate parasite infection and host cellular immune responses starting 1 day postexposure (dpe). We recovered live parasites from stickleback body cavities already 24 hr after exposure. Infection rates increased up to 50% and did not change from 4 dpe onwards. Thus, not all parasites had reached the body cavity at the early time points and clearance of the parasite at later time points did not occur. Stickleback head kidney leucocytes (HKLs) did not show distinct signs of activation and lymphocyte proliferation, granulocyte‐to‐lymphocyte ratios and respiratory burst activity of infected sticklebacks did not deviate from controls significantly. The immune system was activated only late, as indicated by an increase in the total count of HKL relative to stickleback weight (HKL per mg fish), which was significantly elevated in infected fish 32 dpe. S. solidus seems to evade leucocyte activity early during infection facilitating its establishment in the hosts' body cavity. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
01407775
Volume :
41
Issue :
11
Database :
Academic Search Index
Journal :
Journal of Fish Diseases
Publication Type :
Academic Journal
Accession number :
132394280
Full Text :
https://doi.org/10.1111/jfd.12876