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Diabetes is associated with decreased migraine risk: A nationwide cohort study.
- Source :
-
Cephalalgia . Oct2018, Vol. 38 Issue 11, p1759-1764. 6p. 5 Charts. - Publication Year :
- 2018
-
Abstract
- Background Results from studies on diabetes and migraine risk are conflicting, which may be due to methodological limitations. Prospective studies with long follow-up could increase our understanding of the relationship between the two diseases. Method We performed a cohort study including the whole Norwegian population alive on 01.01.2004, using prescriptions registered in the Norwegian prescription database to identify individuals developing type 1 diabetes, type 2 diabetes and migraine during follow-up (10 years). We used Cox proportional hazards regression to estimate rate ratios with corresponding 95% confidence intervals for the effect of diabetes on migraine risk, adjusting for age, sex, and educational level. Result We identified 7,883 type 1 diabetes patients and 93,600 type 2 patients during the study period. Type 1 diabetes was significantly associated with a subsequent decreased migraine risk during follow-up in the age- and sex-adjusted analyses (0.74; 0.61-0.89). Type 2 diabetes was also associated with a significantly lower migraine risk (0.89; 0.83-0.95). Further adjustment for educational level yielded similar results for both diabetes. Conclusion Both type 1 and type 2 diabetes were significantly associated with a decreased risk of migraine. This suggests that diabetes or diabetes treatment may have a protective effect on the development of migraine. [ABSTRACT FROM AUTHOR]
- Subjects :
- *DIABETES
*HEADACHE
*INSULIN resistance
*EPIDEMIOLOGY
MIGRAINE risk factors
Subjects
Details
- Language :
- English
- ISSN :
- 03331024
- Volume :
- 38
- Issue :
- 11
- Database :
- Academic Search Index
- Journal :
- Cephalalgia
- Publication Type :
- Academic Journal
- Accession number :
- 132435395
- Full Text :
- https://doi.org/10.1177/0333102417748573