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Effects of ex vivo aging and storage temperature on blood viscosity.
- Source :
-
Clinical Hemorheology & Microcirculation . 2018, Vol. 70 Issue 2, p155-172. 18p. - Publication Year :
- 2018
-
Abstract
- BACKGROUND: Research on hemorheology is driven in part by its significance in blood diseases and the possible use of hemorheology as a diagnostic tool. However, existing data on blood rheology are limited largely to measurements of steady shear behavior often with varying measurement protocols and insufficient characterization of the physiology. OBJECTIVE: The effects of ex vivo aging and environmental conditions on blood viscosity are investigated to improve standards for hemorheology measurements. METHODS: Measurements on the viscosity of blood from nine healthy donors are obtained and the physiological state of the blood determined. Steady and transient shear measurements are reported as a function of time from withdrawal. The effect of transportation temperature is also assessed. RESULTS: Blood transported at 4 °C may exhibit anomalous viscosity variations for short to intermediate times, as opposed to blood transported at room temperature. A time of approximately 3.0 hours was identified as the maximum time after the initial test that accurate rheological tests can be conducted on blood samples. CONCLUSIONS: Measurement protocol and time limit guidelines are established for conducting accurate rheological measurements on blood. [ABSTRACT FROM AUTHOR]
- Subjects :
- *BLOOD viscosity
*HEMORHEOLOGY
*AGING
*BLOOD transportation
*BLOOD flow
Subjects
Details
- Language :
- English
- ISSN :
- 13860291
- Volume :
- 70
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Clinical Hemorheology & Microcirculation
- Publication Type :
- Academic Journal
- Accession number :
- 132546069
- Full Text :
- https://doi.org/10.3233/CH-170330