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ABO 血型不合活体肝移植术后疗效的 Meta 分析.
- Source :
-
Organ Transplantation / Qi Guan Yi Zhi . Jul2018, Vol. 9 Issue 4, p261-267. 7p. - Publication Year :
- 2018
-
Abstract
- Objective To systematically evaluate the clinical efficacy of ABO-incompatible living donor liver transplantation (ABO-I LDLT) and compare with ABO-compatible LDLT (ABO-C LDLT). Methods A systematic search of multiple databases at home and abroad was conducted to retrieve the literatures related to the statistical comparison of clinical efficacy between ABO-I LDLT and ABO-C LDLT. The literature screening was conducted, the quality of literatures was evaluated and data extraction was performed. Using Rev Man 5.3 software, a Meta-analysis was performed by random effect model or fixed effect model. Results A total of 432 articles were searched, and 6 articles published in English were eventually included according to the inclusion criteria. The Meta-analysis demonstrated that there was no significant difference in the postoperative 1-, 3- and 5-year survival rate of the recipients and grafts and the incidence of rejection responses between the ABO-I LDLT and ABO-C LDLT groups (all P≥0.05). The incidence of postoperative biliary complications and hepatic artery embolization in the ABO-I LDLT group was significantly higher than that in the ABO-C LDLT group [odds ratio (OR) =2.08, 95% confidence interval (CI) 1.25-3.45, P=0.005; OR=2.24, 95%CI 1.03-4.89, P=0.04]. Conclusions Compared with the ABO-C LDLT, ABO-I LDLT yields lower clinical efficacy, whereas it is still an effective method for the treatment of end-stage liver disease. [ABSTRACT FROM AUTHOR]
Details
- Language :
- Chinese
- ISSN :
- 16747445
- Volume :
- 9
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Organ Transplantation / Qi Guan Yi Zhi
- Publication Type :
- Academic Journal
- Accession number :
- 132836277
- Full Text :
- https://doi.org/10.3969/j.issn.1674-7445.2018.04.004