I2/Fe(NO3)3·9H2O-catalyzed oxidative synthesis of aryl carboxylic acids from aryl alkyl ketones and secondary benzylic alcohols.

Authors :: Xu, Liang
Chen, Yingying
Shen, Zhenlu
Wang, Yuru
Li, Meichao
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Dec2018, Vol. 59 Issue 49, p4349-4354. 6p.
Publication Year :: 2018
Abstract: Graphical abstract Highlights • Oxidation of aryl alkyl ketones and secondary benzylic alcohols into aryl carboxylic acids. • Iodine and Fe(NO 3) 3 ·9H 2 O as the catalysts, DMSO and oxygen as the oxidants. • Moderate to excellent yields can be obtained (up to 91%). Abstract An interesting and convenient procedure for the oxidative transformation of aryl alkyl ketones and secondary benzylic alcohols to aryl carboxylic acids has been developed. By using iodine and Fe(NO 3) 3 ·9H 2 O as the catalysts, DMSO and oxygen as the oxidants, the desired aryl carboxylic acids were synthesized in moderate to excellent yields (up to 91%). [ABSTRACT FROM AUTHOR]

Subjects :: *CARBOXYLIC acids
*KETONES
*ALCOHOLS (Chemical class)
*IODINE
*CHEMICAL yield

Language :: English
ISSN :: 00404039
Volume :: 59
Issue :: 49
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 132969163
Full Text :: https://doi.org/10.1016/j.tetlet.2018.10.060

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