Structural insight into precursor tRNA processing by yeast ribonuclease P.

The article focuses on a study according to which all Ribonuclease P (RNase P) ribozymes share a substrateinduced catalytic mechanism of pre-RNA processing. It mentions that RNase P is a ribonucleoprotein complex, composed of a single catalytic RNA components. It states that the Rpr1 RNA adopts an extended single-layered conformation that maintains a central helical core but lacks longrange RNA-RNA interactions that are essential for structural stability in bacterial RNase P.