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Alloy-structured Au-Co bimetallic nanoparticles-decorated graphene oxide as an efficient electrochemiluminescence sensing platform for sensitive detection of glucose in human serum.
- Source :
-
Materials Letters . Feb2019, Vol. 236, p476-479. 4p. - Publication Year :
- 2019
-
Abstract
- Highlights • The Au-Co/GO was synthesized by one-step on site chemical reduction strategy. • Au-Co nanoparticles highly dispersed on GO nanosheets are bimetallic nano-alloys. • The as-prepared Au-Co/GO nanohybrid can act as an improved ECL sensing platform. Abstract Herein, we present the synthesis and electrochemiluminescence (ECL) sensing applications of the Au-Co/GO nanocomposite. Au-Co/GO nanocomposite was prepared for the first time by decorating graphene oxide (GO) with alloy-structured Au-Co bimetallic nanoparticles (BNPs) via one-step on site chemical reduction. The obtained nanocomposite was comprehensively characterized and the results showed that alloy-structured Au-Co nanoparticles (NPs) have an average size of 4 nm and are highly dispersed on GO layers. ECL measurement revealed that the as-synthesized Au-Co/GO nanocomposite displays a synergistic effect of the GO and the Au-Co BNPs on luminol-H 2 O 2 ECL signal. Further immobilization of glucose oxidase (GOD) onto the Au-Co/GO modified electrode afforded a effective ECL glucose sensor which displayed a dynamic range of 1–100 µM with a satisfactory detection limit of 0.18 μM. Furthermore, the developed enzymatic sensors were successfully applied for monitoring glucose in real human samples. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 0167577X
- Volume :
- 236
- Database :
- Academic Search Index
- Journal :
- Materials Letters
- Publication Type :
- Academic Journal
- Accession number :
- 133115328
- Full Text :
- https://doi.org/10.1016/j.matlet.2018.10.165