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Fetal Lymphangioma: Prenatal diagnosis on ultrasound, treatment, and prognosis.
- Source :
-
European Journal of Obstetrics & Gynecology & Reproductive Biology . Dec2018, Vol. 231, p268-273. 6p. - Publication Year :
- 2018
-
Abstract
- <bold>Objective: </bold>To investigate the characteristics of fetal lymphangioma, including their location, imaging features, prenatal and differential diagnoses, treatment, and prognosis.<bold>Study Design: </bold>Imaging data of 79 patients with fetal lymphangioma treated at our hospital were obtained. Imaging modalities included prenatal and post-natal magnetic resonance imaging (MRI), prenatal and post-natal color Doppler ultrasound, and post-natal contrast-enhanced computed tomography (CT). Modalities of delivery and treatment were selected according to the location and size of lymphangioma.<bold>Results: </bold>Among the 133,322 fetuses of 130,202 pregnant women examined at our hospital, 5 fetuses were misdiagnosed and the diagnosis was missed in 5 fetuses prenatally. Finally, 79 had lymphangioma, confirmed by ultrasound, MRI, post-natal CT, and pathological results obtained postoperatively or on autopsy. The diagnostic coincidence rate of lymphangioma was 88.1% (74/84 cases). Of the 79 fetuses with a lymphangioma, septation of the mass was identified in 66 cases (83.54%), with no evidence of septation in the remaining 13 fetuses (16.46%). With regard to location, the lymphangioma was located in the neck in 50 fetuses (63.29%). Interventional sclerotherapy, using bleomycin, was performed in 22 neonates, of which 3 underwent ex utero intrapartum treatment (EXIT) due to evidence of airway or esophageal obstruction (16 patients underwent expectant management; 7 surgical operation). Thirty-two fetuses underwent medical termination and 2 fetuses died in-utero. Of the 16 patients who had expectant treatment, the lesions retroregressed during the intra-uterine period in 7 fetuses, before the post-natal age of 6 months in 4 neonates, and before the age of 2 years in 3 neonates. Of the 7 neonates who were treated surgically, relapse occurred in 1 case, which required re-operation.<bold>Conclusions: </bold>Prenatal ultrasound provides a clear differential diagnosis of fetal lymphangioma. Interventional therapy should be the first-choice treatment for neonates with a lymphangioma confirmed postnatally. [ABSTRACT FROM AUTHOR]
- Subjects :
- *LYMPHANGIOMAS
*PROGNOSIS
*DIAGNOSIS
*PRENATAL diagnosis
*PATIENT education
Subjects
Details
- Language :
- English
- ISSN :
- 03012115
- Volume :
- 231
- Database :
- Academic Search Index
- Journal :
- European Journal of Obstetrics & Gynecology & Reproductive Biology
- Publication Type :
- Academic Journal
- Accession number :
- 133319397
- Full Text :
- https://doi.org/10.1016/j.ejogrb.2018.10.018