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Migraine and Markers of Carotid Atherosclerosis in Middle‐Aged Women: A Cross‐Sectional Study.
- Source :
-
Headache: The Journal of Head & Face Pain . Jan2019, Vol. 59 Issue 1, p77-85. 9p. 1 Diagram, 2 Charts. - Publication Year :
- 2019
-
Abstract
- Objective: This study evaluated the association between migraine and the markers of carotid artery disease. Background: Migraine increases the risk of cardiovascular events, but its relationship with vascular dysfunction is unclear. Methods: In this cross‐sectional study, middle‐aged women with no known cardiovascular diseases underwent clinical, neurological, and laboratory evaluations; pulse wave velocity (PWV) assessment; and carotid artery ultrasonography. We divided the participants based on the presence of migraine and, further, based on the type of migraine. Associations between migraine and carotid thickening (intima‐media thickness >0.9 mm), carotid plaques, or arterial stiffening (PWV >10 m/s) were evaluated using a multiple regression analysis. Results: The study comprised 112/277 (40%) women with migraine, of whom 46/277 (17%) reported having an aura. Compared to the non‐migraineurs, the migraine with aura group had an increased risk of diffuse carotid thickening (3/46 [6.8%] vs 2/165 [1.3%], adjusted OR = 7.12, 95% CI 1.05–48.49). Migraine without aura was associated with a low risk of carotid plaques (3/66 [4.7%] vs 26/165 [16.7%], adjusted OR = 0.28, 95% CI 0.08–0.99) and arterial stiffening (21/66 [34.4%] vs 82/165 [51.2%], adjusted OR = 0.39, 95% CI 0.19–0.79). There were no correlations between migraine characteristics and arterial stiffness or carotid thickness measurements. Conclusion: Migraine with aura is associated with an increased risk of carotid thickening, and migraine without aura is associated with a low risk of carotid plaques and arterial stiffening. [ABSTRACT FROM AUTHOR]
- Subjects :
- *CAROTID artery diseases
*ARTERIAL diseases
*BLOOD pressure
*CAROTID artery
*CONFIDENCE intervals
*CLINICAL pathology
*NEUROLOGIC examination
*SENSES
*WOMEN'S health
*MULTIPLE regression analysis
*CROSS-sectional method
*ODDS ratio
*MIDDLE age
*DISEASE risk factors
*DIAGNOSIS
MIGRAINE complications
Subjects
Details
- Language :
- English
- ISSN :
- 00178748
- Volume :
- 59
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Headache: The Journal of Head & Face Pain
- Publication Type :
- Academic Journal
- Accession number :
- 133687044
- Full Text :
- https://doi.org/10.1111/head.13460