Recent advances and progress of fluorescent bio-/chemosensors based on aggregation-induced emission molecules.

Abstract Aggregation-induced emission (AIE) should be a unique and abnormal fluorescence phenomenon that has attracted increasing research interest over the past decades. Since its discovery by Tang et al., a number of AIE-active molecules with different structure, functional groups and optical properties have been reported. These AIE-active molecules can be further utilized to fabricate various functional materials, which have exhibited great potential for different applications. By taking advantage of this AIE feature (quenching in solution but emission in aggregation state), various bio-/chemosensors have been constructed for detection of relation biological and chemical species. Although some review items on these aspects have been summarized previously, some recent advances and development about targeted biosensor are not included. In this review article, the recent advances and progress in the construction of AIE-active luminogens based fluorescent bio-/chemosensors has been summarized. The challenge and further development of the construction of AIE-active molecules based bio-/chemosensors are also highlighted. Graphical abstract Image 1 Highlights • Design and fabrication of sensors based on AIEgens. • AIEgens could be used for chemosensor. • AIEgens could be used for biomosensor • The utilization of AIEgens for various biomedical applications. [ABSTRACT FROM AUTHOR]