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Colorimetric and fluorescent sensing of Al3+ by a new 2-hydroxynaphthalen based Schiff base "Off-On" chemosensor.
- Source :
-
Journal of Luminescence . Mar2019, Vol. 207, p78-84. 7p. - Publication Year :
- 2019
-
Abstract
- Abstract A new 2-hydroxynaphthalen based Schiff base colorimetric and fluorescence chemosensor, H 2 acid}, for selective sensing of Al3+ ions has been synthesized and characterize by different physico-chemical and spectroscopic techniques. The probe shows enhanced fluorescence and significant color change from bright yellow to colorless in the presence of Al3+ ions in methanol-water (9:1 v/v) solution, without interference from other metal ions. The binding mode of H 2 L with Al3+ was studied by UV–vis, fluorescence titration, job's plot analysis, and ESI-MS. The probe acts as a bidentate ligand and interacts with Al3+ ions with a binding constant of K b = 1.546 × 105 M−1. The limit of detection for Al3+ is found to be 6.4 × 10−7 M. The cytotoxicity of the probe has been evaluated by MTT assay on MCF-7 cell line, indicating more than 92% cell viability in the concentration range of 1.25–50 μM with no serious cytotoxicity on cells. Live cell imaging study clearly indicates that the accumulation of Al3+ in living cells can be detected by H 2 L. Graphical abstract fx1 [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00222313
- Volume :
- 207
- Database :
- Academic Search Index
- Journal :
- Journal of Luminescence
- Publication Type :
- Academic Journal
- Accession number :
- 133871324
- Full Text :
- https://doi.org/10.1016/j.jlumin.2018.10.115