DETECTION OF COAGULASE PRODUCTION VARIABILITY AMONG STAPHYLOCOCCUS AUREUS ISOLATES OF HUMAN AND ANIMAL ORIGINS.

Staphylococcus aureus is one of the most important pathogens causing various clinical and sub clinical infections in human and animals and is often associated with hospital acquired infections in hospitalized patients. This study was attempted to detect variations in coagulase reaction in relation varied S. aureus bacterial sources and varied plasma sources. Of the genotypically confirmed 157 S. aureus isolates from human and animal sources, 153 (97.4%) isolates were found to be coagulase producers while four (2.5%) isolates did not produce coagulase at 24 hour recording with any of the plasmas. Human plasma showed the best coagulation reaction followed by plasma from camel, poultry, sheep, goat and cattle in decreasing order. It was also observed from a particular species stronger coagulation reaction with plasma from same species. The analysis of coagulase reactions suggested that coagulation activity not only depended on source of bacterial isolate but also on source of plasma. [ABSTRACT FROM AUTHOR]