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Management of Typical and Atypical Pulmonary Carcinoids Based on Different Established Guidelines.

Authors :
Gosain, Rohit
Mukherjee, Sarbajit
Yendamuri, Sai S.
Iyer, Renuka
Source :
Cancers. Dec2018, Vol. 10 Issue 12, p510. 1p.
Publication Year :
2018

Abstract

Neuroendocrine tumors (NETs) are a group of malignancies that originated from neuroendocrine cells, with the most common sites being lungs and the gastrointestinal tract. Lung NETs comprise 25% of all lung malignancies. Small cell lung cancer is the most common form of lung NETs, and other rare forms include well-differentiated typical carcinoids (TCs) and poorly differentiated atypical carcinoids (ACs). Given the paucity of randomized studies, rational treatment is challenging. Therefore, it is recommended that these decisions be made using a multidisciplinary collaborative approach. Surgery remains the mainstay of treatment, when feasible. Following surgery, various guidelines offer different recommendations in the adjuvant setting. In this paper, we describe the adjuvant management of lung NETs, as recommended by different guidelines, and highlight their differences. In addition to that, we also discuss the management of metastatic lung NETS, including the use of peptide receptor radionucleotide therapy. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20726694
Volume :
10
Issue :
12
Database :
Academic Search Index
Journal :
Cancers
Publication Type :
Academic Journal
Accession number :
134074734
Full Text :
https://doi.org/10.3390/cancers10120510