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Behavioral Strategies to Lower Postprandial Glucose in Those with Type 2 Diabetes May Also Lower Risk of Coronary Heart Disease.
- Source :
-
Diabetes Therapy . Feb2019, Vol. 10 Issue 1, p277-281. 5p. - Publication Year :
- 2019
-
Abstract
- Introduction: Efforts to lower glycosylated hemoglobin (A1c) in patients with type 2 diabetes (T2D) are intended to reduce the risk of diabetic complications, but A1c is not the only factor contributing to this risk. Consequently, we re-analyzed published data from a broad-spectrum lifestyle intervention that lowered A1c to assess its effectiveness in lowering the overall risk of two complications of T2D, namely, coronary heart disease (CHD) and stroke.Methods: Data from 37 adults who participated in a randomized clinical trial of a lifestyle intervention intended to reduce postprandial glucose (PPG) were re-analyzed for their pre- and post-treatment risk of CHD and stroke using the T2D-specific UK Prospective Diabetes Study (UKPDS) v2.0 risk algorithm.Results: Compared to participants who received routine care, those using the lifestyle intervention had a significantly greater reduction in 10-year risk for CHD, but not for stroke.Conclusion: These secondary analyses suggest that broad-spectrum lifestyle interventions that focus on lowering PPG may lower the risk of future CHD, which could guide future research.Trial Registration: ClinicalTrials.gov ID: NCT02432391. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 18696953
- Volume :
- 10
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Diabetes Therapy
- Publication Type :
- Academic Journal
- Accession number :
- 134310546
- Full Text :
- https://doi.org/10.1007/s13300-018-0554-6